Table 1.
Baseline characteristics and outcomes by type of anticoagulation
| Variable | All n = 921 (%) | Prior_ACn = 33 (%) | Prophy n = 672 (%) | New_ACn = 191 (%) | No_ACn = 25 (%) | p-value | |
|---|---|---|---|---|---|---|---|
| Age (year, median) | 62.0 | 68.0 | 62.0 | 62.0 | 64.0 | 0.303 | |
| Sex | Female | 347 (37.7) | 13 (39.4) | 259 (38.5) | 68 (35.6) | 7 (28) | 0.677 |
| Male | 574 (62.3) | 20 (60.6) | 418 (61.5) | 123 (64.4) | 18 (72) | ||
| Race | Black | 260 (33.8) | 17 (56.7) | 181 (32.4) | 55 (34.2) | 7 (36.8) | 0.210 |
| Asian | 17 (2.2) | 11 (2) | 5 (3.1) | 1 (5.3) | |||
| Hispanic | 472 (61.4) | 13 (43.3) | 350 (62.6) | 99 (61.5) | 10 (52.6) | ||
| Caucasian | 20 (2.6) | 17 (3) | 2 (1.2) | 1 (5.3) | |||
| BMI (kg/m2, mean) | 30.4 | 30.1 | 30.5 | 30.6 | 27.5 | 0.231 | |
| D-dimer at admission (ng/mL, mean) | 3190 | 2149 | 2550 | 5217 | 2990 | < 0.001 | |
| Peak D-dimer level (ng/mL, mean) | 6206 | 4231 | 3652 | 14317 | 3173 | < 0.001 | |
| Intubated | 323 (35.1) | 11 (33.3) | 188 (28) | 119 (62.6) | 2 (20) | < 0.001 | |
| Successfully extubated† | 53 (16.4) | 2 (18.1) | 24 (12.7) | 27 (22.6) | 0 | 0.077 | |
| Median days on mechanical ventilation (Range)‡ | 4 (1–14) | 3 | 3 | 4 | 0 | 0.834 | |
| Intra-hospital bleeding | 35 (4.1) | 3 (10) | 11 (1.7) | 19 (11.4) | 2 (10.5) | < 0.001 | |
| Length of stay (days, median)* | 9.0 | 8.8 | 7.4 | 15.3 | 5.6 | < 0.001 | |
Abbreviations: Prior_AC patients on anticoagulation prior to admission and continued during hospitalization, Prophy patients who received only prophylactic anticoagulation, New_AC patients who were started on therapeutic anticoagulation during hospitalization, No_AC patients who did not receive any anticoagulation, BMI body mass index
†Percentages are calculated for intubated patients only
‡Only in extubated patients
*Only in patients who were discharged from the hospital