Hypertension, proteinuria, and ischemic glomeruli in Klf17−/− mice. (A) Systolic blood pressure (BP) in nonpregnant (NP) and pregnant (G12.5 and G18.5) WT and Klf17−/− (KO) mice. n = 8 to 14 per group. (B) Urinary protein levels in NP and pregnant (G12.5 and G18.5) WT and KO mice. n = 7 to 16 per group. (C) Glomerular histology in PAS-stained and Masson’s trichrome-stained renal sections from NP and pregnant (G12.5 and G18.5) WT and KO mice. (Scale bars, 20 μm). (D) Glomerular red blood cells (RBC) were counted in renal sections from NP and pregnant (G12.5 and G18.5) WT and KO mice. In A, B, and D, data are presented as mean ± SEM; P values were analyzed by ANOVA; ns, not significant.