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. Author manuscript; available in PMC: 2020 Oct 30.
Published in final edited form as: Nature. 2020 Apr 30;583(7816):459–468. doi: 10.1038/s41586-020-2286-9

Extended Data Figure 11. Astemizole is a potent Sigma2 Receptor Ligand.

Extended Data Figure 11.

Concentration response curves of astemizole from radio-ligand displacement assays for (a) the Sigma2 (95 nM IC50) and (b) the Sigma1 (1.3 uM IC50) receptors are shown. Data=mean±SEM; n= 4 independent assays on each receptor.