Fig. 4.

A single dose of PDX decreased murine gut carriage of EAEC. Twenty-four hours after inoculation with EAEC, mice were gavaged with PDX phage at an m.o.i. of 100 or an equal volume of buffer control. No colonies were detected in phage-only control mice across the 5-day period. Statistical analysis was carried out to compare PDX-treated mice to control-treated mice at each indicated day (n=14 animals per day, day 2, P=0.0097; day 3, P=0.0214; day 5, P=0.0016). Each error bar is constructed using 1 standard deviation from the mean. Levels connected by an asterisk are statistically significantly different (P<0.05).