Table 3.
Sex Differences Donepezil Group: Serum Concentration and BMI of Male and Female Participants
Male | Female | p-value | |
---|---|---|---|
Serum concentration donepezil (in ng/mL) | 33.1 ± 12.0 (12.95–56.65) | 44.2 ± 18.44 (14.85–87.55) | 0.021 |
Serum concentration on daily dose of 10mg | 34.8 ± 11.17 (18.75–56.65) | 48.0 ± 16.83 (23.4–87.55) | 0.004 |
Body weight (in kg) | 74.7± 5.9 (60–83) | 64.8 ± 9.1 (50–83) | <0.001 |
BMI (in kg/m2) | 23.8 ± 2.33 (17.2–26.5) | 24.0 ± 3.79 (18.6–34.5) | 0.762 |
Notes: Where applicable: mean ± standard deviation (minimum−maximum). p-value calculated from Mann–Whitney-U-test
Abbreviations: ng, nanogram; mL, milliliter; mg, milligram; kg, participants’ weight in kilogram; BMI, body mass index.