Table 4.

Prediction of Serum Concentration of Donepezil: Multivariate Regression Model

	Beta	p-value
Gene dose	−0.342	0.019
Daily dose	0.378	0.003
CYP2D6-inhibitors	0.213	0.071
Age	0.160	0.165
Sex	−0.532	<0.001
Duration of AChE-I treatment	0.285	0.038
Time since last dosing (in h)	−0.016	0.900

Notes: n=47; corr. R²= 0.473; p <0.001

Abbreviations: AChE-I, acetylcholinesterase inhibitor; h, hours.