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. 2020 Apr 8;41(6):775–820. doi: 10.1210/endrev/bnaa008

Figure 4.

Figure 4.

Biosynthesis of catecholamines in (A) chromaffin cells of adrenal medulla and (B) sympathetic nerve cells. TH, tyrosine hydroxylase; L-AADC, aromatic L-amino-acid decarboxylase; DBH, dopamine- β -hydroxylase; PNMT, phenylethanolamine-N-methyltransferase (108). Reproduced from van Berkel A, Lenders JW, Timmers HJ. Diagnosis of endocrine disease: Biochemical diagnosis of phaeochromocytoma and paraganglioma. Eur J Endocrinol 2014; 170:R109-119.