Table 3.
Characteristics of adrenal incidentalomas: age, sex balance, tumor size and lateralization.
| Study (ref) | Year | No. of patients | Mean Age (years) | Female/Male | Tumor size (median, mm) | Unilateral | Right | Left | Bilateral |
|---|---|---|---|---|---|---|---|---|---|
| Virkkala et al. (46) | 1989 | 20 | 59 | 1.4 | 23 | 14 | N/A | N/A | 5 |
| Herrera et al. (39) | 1991 | 342 | 62 | 1.5 | 25 | N/A | |||
| Aso and Homma (47) | 1992 | 210 | 53 | 0.7 | 49 | N/A | |||
| Reincke et al. (48) | 1992 | 68 | 59 | 1.6 | 32 | N/A | |||
| Caplan et al. (40) | 1994 | 26 | 66 | 1.9 | NR | N/A | |||
| Osella et al. (49) | 1994 | 45 | 58 | 1.4 | 30 | N/A | |||
| Seppel and Schlaghecke (50) | 1994 | 52 | 56 | 1.7 | 30 | N/A | |||
| Ambrosi et al. (51) | 1995 | 32 | 55 | 2.5 | 27 | 27 | 22 | 5 | 5 |
| Bencsik et al. (52) | 1995 | 63 | 27—85 | 1.1 | 14—25 | N/A | |||
| Flecchia et al. (53) | 1995 | 32 | 57 | 1.3 | 37 | N/A | |||
| Bardet et al. (54) | 1996 | 35 | N/A | N/A | 26 | 35 | N/A | N/A | 0 |
| Linos et al. (55) | 1996 | 57 | 49 | 1.3 | 59 | N/A | |||
| Bastounis et al. (56) | 1997 | 86 | 61 | 1.5 | 41 | 81 | 45 | 36 | 5 |
| Bondanelli et al. (57) | 1997 | 38 | 58 | 1.4 | 26 | 28 | 16 | 12 | 10 |
| Kasperlik-Zeluska et al. (58) | 1997 | 208 | 52 | 2.5 | 8—210 | 172 | 106 | 66 | 36 |
| Terzolo et al. (59) | 1995 | 45 | 55 | 1.4 | 31 | N/A | |||
| Proye et al. (60) | 1998 | 103 | N/A | N/A | N/A | N/A | |||
| Murai et al. (61) | 1999 | 59 | N/A | N/A | N/A | N/A | |||
| Tütüncü and Gedik (62) | 1999 | 33 | 51 | 1.2 | 51 | N/A | |||
| Favia et al. (63) | 2000 | 158 | 58 | 1.2 | 44 | 158 | 74 | 84 | 0 |
| Mantero and Arnaldi (64) | 2000 | 208 | N/A | N/A | N/A | N/A | |||
| Rossi et al. (65) | 2000 | 50 | 54 | 1.7 | 33 | 47 | 28 | 19 | 3 |
| Mantero et al. (66) | 2000 | 1004 | 58 | 1.4 | 30 | 903 | 596 | 307 | 101 |
| Tanabe et al. (67) | 2001 | 38 | N/A | N/A | N/A | N/A | |||
| Barzon et al. (68) | 2002 | 284 | 56 | 1.5 | 36 | N/A | |||
| Bülow and Ahrén (84) | 2002 | 381 | 64 | 1.3 | 30 | 359 | N/A | N/A | 22 |
| Tsvetov et al. (69) | 2007 | 100 | 62 | 0.9 | 24 | 77 | 34 | 43 | 23 |
| Bhargav et al. (70) | 2008 | 53 | 41 | 1.1 | 78 | 51 | 30 | 21 | 2 |
| Kasperlik-Załuska et al. (71) | 2008 | 1444 | 10—87 | 2.7 | 10—230 | 1175 | 709 | 466 | 269 |
| Song et al. (42) | 2008 | 3307 | 64 | N/A | 20 | N/A | |||
| Vassilatou et al. (72) | 2009 | 77 | 57 | 2.5 | 25 | 59 | 22 | 37 | 17 |
| Comlekci et al. (73) | 2010 | 376 | 55 | 2.3 | 25 | 313 | N/A | N/A | 54 |
| Anagnostis et al. (74) | 2010 | 64 | 62 | 1.9 | N/A | N/A | |||
| Giordano et al. (75) | 2010 | 118 | 62 | 1.5 | 22 | 102 | 57 | 45 | 16 |
| Yener et al. (76) | 2010 | 317 | 55 | 2.7 | 24 | 362 | 190 | 172 | 45 |
| Muth et al. (77) | 2011 | 226 | 67 | 1 | 24.1 | N/A | |||
| Cho et al. (78) | 2013 | 282 | 57 | 0.7 | 23 | 261 | 103 | 158 | 21 |
| Di Dalmazi et al. (79) | 2014 | 129 | 61 | 1.5 | 21 (max) | 92 | N/A | N/A | 22 |
| Hong et al. (80) | 2017 | 1149 | 54 | 0.8 | 18 | N/A | |||
| Ahn et al. (81) | 2018 | 1005 | 44 | 0.7 | 17 | 902 | 308 | 594 | 103 |
| Akkuş et al. (82) | 2018 | 229 | 52 | 1.7 | 48 | 202 | N/A | N/A | 27 |
| Goh et al. (83) | 2018 | 228 | 61 | 1.5 | 18 | 196 | 70 | 126 | 32 |
| Median value for all studies | 64 | 57.5 | — | 30 | — | — | — | — |
Abbreviation: N/A, data not available.