Table 4.
Criteria | Scoring points | |
---|---|---|
0 | 1 | |
Nuclear grade (Fuhrmann nuclear grade system) | I/II | III/IV |
Mitoses | <6/10 HPF | ≥6/10 HPF |
Atypical mitoses | − | + |
Clear cell component | <25% | ≥25% |
Diffuse architecture | <1/3 | ≥1/3 |
Confluent necrosis | − | + |
Venous invasion | − | + |
Sinusoidal invasion | − | + |
Capsular infiltration | − | + |
Adapted from references (111-113).
Abbreviation: HPF, high power fields.