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. 2020 Jul 20;98(8):skaa232. doi: 10.1093/jas/skaa232

Table 6.

Messenger RNA abundance of IGF1R, IGF2, IGF2R, GYS-1, IRS-1, INSR, SREBP-1c, and LEPR in muscle samples of female and male fetuses harvested at 111 d of gestation from sows submitted to 4 different supplementation treatments

Gene1 Sex Treatments2 SEM P-value
CON BEEF B+S SUGAR Average Sex Trt Sex Trt × Sex
IGF1R Female 4.97 6.54 2.64 6.74 5.22 2.40 0.52 0.29 0.97
Male 3.41 4.34 2.36 4.28 3.59
Average Trt 4.19 5.44 2.49 5.51
IGF2 Female 1.53 2.19 1.19 0.92 1.46 0.68 0.02 0.25 0.18
Male 3.81 2.17 1.07 0.87 1.98
Average Trt 2.67a 2.19ab 1.13b 0.89b
IGF2R Female 1.56 5.75 5.48 4.86 0.99 2.32 0.29 0.89 0.92
Male 2.65 4.65 5.93 3.68 1.00
Average Trt 2.10 5.20 5.71 4.27
GYS-1 Female 2.41 1.98 1.44 2.19 2.01 0.91 0.96 0.45 0.69
Male 2.38 1.99 3.24 2.29 2.48
Average Trt 2.39 1.99 2.34 2.24
IRS1 Female 0.26 0.92 0.29 0.28 0.44 0.29 0.46 0.48 0.44
Male 0.22 0.29 0.46 0.24 0.30
Average Trt 0.24 0.60 0.38 0.26
INSR Female 0.61 0.65 0.63 0.62 0.63 0.06 0.58 0.84 0.76
Male 0.59 0.64 0.71 0.59 0.64
Average Trt 0.60 0.65 0.67 0.61
SREBP-1c Female 1.32 1.52 3.81 2.54 2.29a 0.48 <0.01 0.06 0.12
Male 1.46 1.64 2.11 1.54 1.69b
Average Trt 1.39a 1.58a 2.96b 2.04a
LEPR Female 0.31 0.45 0.19 0.48 0.36 0.17 0.67 0.71 0.59
Male 0.46 0.32 0.24 0.24 0.32
Average Trt 0.38 0.39 0.22 0.36

1 IGF1R, insulin-like growth factor 1 receptor; IGF2, insulin-like growth factor 2; IGF2R, insulin-like growth factor 2 receptor; GYS-1, glycogen synthase 1; IRS-1, insulin receptor substrate 1; INSR, insulin receptor; SREBP-1C, sterol regulatory element binding protein 1c; LEPR, leptin receptor.

2CON, control supplement (378 g/d corn–soybean meal); BEEF, cooked ground beef supplement (330 g/d); B+S, cooked ground beef (165 g/d) and granulated sugar (129 g/d); SUGAR, granulated sugar supplement (255 g/d).

abMeans without a common superscript differ (P ≤ 0.05).