Table 6.
Messenger RNA abundance of IGF1R, IGF2, IGF2R, GYS-1, IRS-1, INSR, SREBP-1c, and LEPR in muscle samples of female and male fetuses harvested at 111 d of gestation from sows submitted to 4 different supplementation treatments
Gene1 | Sex | Treatments2 | SEM | P-value | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
CON | BEEF | B+S | SUGAR | Average Sex | Trt | Sex | Trt × Sex | ||||
IGF1R | Female | 4.97 | 6.54 | 2.64 | 6.74 | 5.22 | 2.40 | 0.52 | 0.29 | 0.97 | |
Male | 3.41 | 4.34 | 2.36 | 4.28 | 3.59 | ||||||
Average Trt | 4.19 | 5.44 | 2.49 | 5.51 | |||||||
IGF2 | Female | 1.53 | 2.19 | 1.19 | 0.92 | 1.46 | 0.68 | 0.02 | 0.25 | 0.18 | |
Male | 3.81 | 2.17 | 1.07 | 0.87 | 1.98 | ||||||
Average Trt | 2.67a | 2.19ab | 1.13b | 0.89b | |||||||
IGF2R | Female | 1.56 | 5.75 | 5.48 | 4.86 | 0.99 | 2.32 | 0.29 | 0.89 | 0.92 | |
Male | 2.65 | 4.65 | 5.93 | 3.68 | 1.00 | ||||||
Average Trt | 2.10 | 5.20 | 5.71 | 4.27 | |||||||
GYS-1 | Female | 2.41 | 1.98 | 1.44 | 2.19 | 2.01 | 0.91 | 0.96 | 0.45 | 0.69 | |
Male | 2.38 | 1.99 | 3.24 | 2.29 | 2.48 | ||||||
Average Trt | 2.39 | 1.99 | 2.34 | 2.24 | |||||||
IRS1 | Female | 0.26 | 0.92 | 0.29 | 0.28 | 0.44 | 0.29 | 0.46 | 0.48 | 0.44 | |
Male | 0.22 | 0.29 | 0.46 | 0.24 | 0.30 | ||||||
Average Trt | 0.24 | 0.60 | 0.38 | 0.26 | |||||||
INSR | Female | 0.61 | 0.65 | 0.63 | 0.62 | 0.63 | 0.06 | 0.58 | 0.84 | 0.76 | |
Male | 0.59 | 0.64 | 0.71 | 0.59 | 0.64 | ||||||
Average Trt | 0.60 | 0.65 | 0.67 | 0.61 | |||||||
SREBP-1c | Female | 1.32 | 1.52 | 3.81 | 2.54 | 2.29a | 0.48 | <0.01 | 0.06 | 0.12 | |
Male | 1.46 | 1.64 | 2.11 | 1.54 | 1.69b | ||||||
Average Trt | 1.39a | 1.58a | 2.96b | 2.04a | |||||||
LEPR | Female | 0.31 | 0.45 | 0.19 | 0.48 | 0.36 | 0.17 | 0.67 | 0.71 | 0.59 | |
Male | 0.46 | 0.32 | 0.24 | 0.24 | 0.32 | ||||||
Average Trt | 0.38 | 0.39 | 0.22 | 0.36 |
1 IGF1R, insulin-like growth factor 1 receptor; IGF2, insulin-like growth factor 2; IGF2R, insulin-like growth factor 2 receptor; GYS-1, glycogen synthase 1; IRS-1, insulin receptor substrate 1; INSR, insulin receptor; SREBP-1C, sterol regulatory element binding protein 1c; LEPR, leptin receptor.
2CON, control supplement (378 g/d corn–soybean meal); BEEF, cooked ground beef supplement (330 g/d); B+S, cooked ground beef (165 g/d) and granulated sugar (129 g/d); SUGAR, granulated sugar supplement (255 g/d).
abMeans without a common superscript differ (P ≤ 0.05).