Table 2. Demographic characteristics and complications of infants with RDS.
| Characteristics | Total (n = 19,442) | 2014 (n = 3,637) | 2015 (n = 4,044) | 2016 (n = 4,061) | 2017 (n = 3,907) | 2018 (n = 3,793) | P value | |
|---|---|---|---|---|---|---|---|---|
| Male | 10,924 (56.2) | 2,040 (56.1) | 2,204 (54.5) | 2,283 (56.2) | 2,239 (57.3) | 2,158 (56.9) | 0.114 | |
| Preterm | 14,922 (76.8) | 2,855 (78.5) | 3,241 (80.1) | 3,135 (77.2) | 2,928 (74.9) | 2,763 (72.8) | < 0.001 | |
| Term | 4,520 (23.2) | 782 (21.5) | 803 (19.9) | 926 (22.8) | 979 (25.1) | 1,030 (27.2) | < 0.001 | |
| Ventilator use | 14,641 (75.3) | 2,695 (74.1) | 3,006 (74.3) | 2,976 (73.3) | 2,924 (74.8) | 3,040 (80.1) | < 0.001 | |
| Pulmonary hemorrhage | 564 (2.9) | 130 (3.6) | 115 (2.8) | 108 (2.7) | 98 (2.5) | 113 (3.0) | 0.062 | |
| Pneumothorax | 1,060 (5.5) | 190 (5.2) | 191 (4.7) | 211 (5.2) | 222 (5.7) | 246 (6.5) | 0.098 | |
| Pneumothorax in term | 409 (9.0) | 54 (6.9) | 46 (5.7) | 89 (9.6) | 99 (10.1) | 121 (11.7) | 0.078 | |
| Pneumothorax in preterm | 651 (4.3) | 136 (4.8) | 145 (4.5) | 122 (3.9) | 123 (4.2) | 125 (4.5) | 0.522 | |
| Pneumothorax with chest tube | 580 (3.0) | 119 (3.3) | 103 (2.5) | 114 (2.8) | 120 (3.1) | 124 (3.3) | 0.256 | |
| PPHN | 1,210 (6.2) | 217 (6.0) | 204 (5.0) | 213 (5.2) | 263 (6.7) | 313 (8.3) | < 0.001 | |
| MAS | 425 (2.2) | 73 (2.0) | 65 (1.6) | 92 (2.3) | 92 (2.4) | 103 (2.7) | 0.014 | |
| BPD | 2,914 (15.0) | 527 (14.5) | 591 (14.6) | 640 (15.8) | 624 (16.0) | 532 (14.0) | 0.067 | |
| PDA | 5,839 (30.0) | 1,140 (31.3) | 1,150 (28.4) | 1,152 (28.4) | 1,246 (31.9) | 1,151 (30.3) | < 0.001 | |
| PDA ligation | 616 (3.2) | 141 (3.9) | 110 (2.7) | 87 (2.1) | 118 (3.0) | 160 (4.2) | < 0.001 | |
| IVH | 2,326 (12.0) | 471 (13.0) | 470 (11.6) | 450 (11.1) | 467 (12.0) | 468 (12.3) | 0.120 | |
| HIE | 191 (1.0) | 16 (0.4) | 25 (0.6) | 27 (1.5) | 58 (1.5) | 65 (1.7) | < 0.001 | |
| PVL | 655 (3.4) | 85 (2.3) | 140 (3.5) | 118 (2.9) | 179 (4.6) | 133 (3.5) | < 0.001 | |
| Death | 1,229 (6.3) | 283 (7.8) | 234 (5.8) | 262 (6.5) | 227 (5.8) | 223 (5.9) | 0.001 | |
Data are presented as number (%).
RDS = respiratory distress syndrome, PPHN = persistent pulmonary hypertension, MAS = meconium aspiration syndrome, BPD = bronchopulmonary dysplasia, PDA = patent ductus arteriosus, IVH = intraventricular hemorrhage, HIE = hypoxic ischemic encephalopathy, PVL = periventricular leukomalacia.