Table 3. Complications of infants with RDS by gestational age group.
| Complications | Gestational age, wk | P value | |||
|---|---|---|---|---|---|
| < 28 (n = 2,774) | 28–31 (n = 4,643) | 32–36 (n = 6,736) | ≥ 37 (n = 4,520) | ||
| Death | 538 (19.4) | 147 (3.2) | 227 (3.4) | 271 (6.0) | < 0.001 |
| Ventilator use | 2,264 (81.6) | 3,553 (76.5) | 5,816 (86.3) | 2,418 (53.5) | < 0.001 |
| Pulmonary hemorrhage | 203 (7.3) | 107 (2.3) | 138 (2.0) | 93 (2.1) | < 0.001 |
| Pneumothorax | 201 (7.2) | 128 (2.8) | 281 (4.2) | 409 (9.0) | < 0.001 |
| Pneumothorax with chest tube | 139 (5.0) | 76 (1.6) | 147 (2.2) | 195 (4.3) | < 0.001 |
| PPHN | 209 (7.5) | 199 (4.3) | 298 (4.4) | 459 (10.2) | < 0.001 |
| BPD | 1,037 (37.4) | 940 (20.2) | 633 (9.4) | 141 (3.1) | < 0.001 |
| PDA | 1,685 (60.7) | 1,801 (38.8) | 1,473 (21.9) | 519 (11.5) | < 0.001 |
| PDA ligation | 325 (11.7) | 131 (2.8) | 95 (1.4) | 22 (0.5) | < 0.001 |
| IVH | 749 (27.0) | 616 (13.3) | 698 (10.4) | 132 (2.9) | < 0.001 |
| HIE | 11 (0.4) | 37 (0.8) | 62 (0.9) | 74 (1.6) | < 0.001 |
| PVL | 113 (4.1) | 265 (5.7) | 209 (3.1) | 51 (1.1) | < 0.001 |
Data are presented as number (%).
RDS = respiratory distress syndrome, BPD = bronchopulmonary dysplasia, PDA = patent ductus arteriosus, IVH = intraventricular hemorrhage, HIE = hypoxic ischemic encephalopathy, PVL = periventricular leukomalacia, PPHN = persistent pulmonary hypertension.