Table 4. Complications of infants with RDS by birth weight group.
| Complications | Birth weight, g | P value | |||
|---|---|---|---|---|---|
| < 1,000 (n = 3,071) | 1,000–1,500 (n = 3,424) | 1,500–2,500 (n = 5,228) | > 2,500 (n = 4,520) | ||
| Death | 585 (19.0) | 103 (3.0) | 106 (2.0) | 271 (6.0) | < 0.001 |
| Ventilator use | 2,521 (82.1) | 2,567 (75.0) | 4,474 (85.6) | 2,418 (53.5) | < 0.001 |
| Pulmonary hemorrhage | 247 (8.0) | 89 (2.6) | 66 (1.3) | 93 (2.1) | < 0.001 |
| Pneumothorax | 226 (7.4) | 104 (3.0) | 149 (2.9) | 409 (9.0) | < 0.001 |
| Pneumothorax with chest tube | 145 (4.7) | 57 (1.7) | 72 (1.4) | 195 (4.3) | < 0.001 |
| PPHN | 264 (8.6) | 133 (3.9) | 192 (3.7) | 459 (10.2) | < 0.001 |
| BPD | 1,129 (36.8) | 832 (24.3) | 472 (9.0) | 141 (3.1) | < 0.001 |
| PDA | 1,853 (60.3) | 1,492 (43.6) | 1,203 (23.0) | 519 (11.5) | < 0.001 |
| PDA ligation | 346 (11.3) | 129 (3.8) | 55 (1.1) | 22 (0.5) | < 0.001 |
| IVH | 786 (25.6) | 531 (15.5) | 543 (10.4) | 132 (2.9) | < 0.001 |
| HIE | 16 (0.5) | 18 (0.5) | 51 (1.0) | 74 (1.6) | < 0.001 |
| PVL | 129 (4.2) | 171 (5.0) | 221 (4.2) | 51 (1.1) | < 0.001 |
Data are presented as number (%).
RDS = respiratory distress syndrome, BPD = bronchopulmonary dysplasia, PDA = patent ductus arteriosus, IVH = intraventricular hemorrhage, HIE = hypoxic ischemic encephalopathy, PVL = periventricular leukomalacia, PPHN = persistent pulmonary hypertension.