Table 3. Indicators of clinical aggravation among COVID-19 patients with initial mild presentation at 5-day intervals after onset of illness in multivariate analysis.

Days after onset of illness	Fever, > 37.5°C	P value	Platelet count, < 130,000/mm3	P value	LDH, > 300 U/L	P value	CRP, > 1 mg/dL	P value
1–5th	4.56 (1.06–19.71)	0.042	-	-	-	-	-	-
6–10th	-	-	12.87 (1.87–88.59)	0.009	-	-	-	-
11–15th	27.22 (3.67–202.04)	0.001	-	-	18.35 (1.98–170.39)	0.010	-	-
16–20th	-	-	-	-	-	-	11.31 (1.78–71.93)	0.010

Data are presented as odds ratio (95% confidence interval).

COVID-19 = coronavirus disease 2019, LDH = lactate dehydrogenase, CRP = C-reactive protein.