Table 2. Positive rate of anti-CagA IgG, IgA, and IgM according to age and year.

Age	IgG, %			P value	IgA, %			P value	IgM, %			P value
	1994–1995	2004–2005	2014–2015		1994–1995	2004–2005	2014–2015		1994–1995	2004–2005	2014–2015
Neonate	73.7	75.0	63.2	0.765	10.5	30.0	0.0	0.021	0.0	15.0	0.0	0.100
1–6 mon	55.0	55.0	25.0	0.112	0.0	5.0	0.0	1.000	0.0	5.0	0.0	1.000
7–12 mon	50.0	31.6	0.0	< 0.001	0.0	5.3	0.0	0.317	0.0	0.0	0.0	-
13–24 mon	45.0	15.0	15.0	0.063	15.0	5.0	0.0	0.310	0.0	0.0	0.0	-
2–4 yr	25.0	17.5	13.9	0.484	2.5	2.5	5.6	0.686	0.0	0.0	0.0	-
5–9 yr	35.0	22.5	15.0	0.132	12.5	12.5	12.5	1.000	0.0	7.5	2.5	0.322
10–14 yr	60.0	35.9	12.5	< 0.001	27.5	30.8	10.0	0.047	2.5	0.0	5.0	0.772
15–19 yr	85.0	52.5	17.5	< 0.001	40.0	35.0	17.5	0.081	2.5	0.0	10.0	0.125
20–29 yr	80.0	72.5	28.9	< 0.001	30.0	52.5	24.4	0.022	2.5	12.5	15.6	0.109
30–39 yr	85.0	77.5	62.5	0.070	67.5	50.0	55.0	0.259	7.5	32.5	12.5	0.010
40–49 yr	62.5	77.5	82.5	0.107	27.5	50.0	52.5	0.049	5.0	20.0	20.0	0.083
50–59 yr	72.5	92.5	89.5	0.034	67.5	72.5	84.2	0.216	27.5	22.5	21.1	0.859
≥ 60 yr	72.5	69.0	75.0	0.829	57.5	48.3	62.5	0.492	22.5	13.8	20.0	0.749

Statistically significant differences according to age and study period are shown in bold.

CagA = cytotoxic-associated gene A, Ig = immunoglobulin.