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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Eur J Gastroenterol Hepatol. 2020 Dec;32(12):1566–1570. doi: 10.1097/MEG.0000000000001681

Table 2.

Patients Characteristics

Factor Overall
N=6,142,504
Wgt N = 30,712,524		 No NASH
N=6,098,714
Wgt N = 30,493,574		 NASH
N=43,790
Wgt N = 218,950		 p-value
Age (years), mean ± se 57.3 ± 0.10 57.3 ± 0.10 54.5 ± 0.11 <0.001a
Age (years), % ± se <0.001c
 18-44 29.3 ± 0.21 29.3 ± 0.21 26.1 ± 0.29
 45-64 29.3 ± 0.12 29.2 ± 0.12 47.2 ± 0.25
 65+ 41.4 ± 0.21 41.5 ± 0.21 26.8 ± 0.31
Gender, % ± se <0.001c
 Male 40.7 ± 0.13 40.6 ± 0.13 42.9 ± 0.29
 Female 59.3 ± 0.13 59.4 ± 0.13 57.1 ± 0.29
Race, % ± se <0.001c
 White 65.1 ± 0.55 65.1 ± 0.55 67.7 ± 0.70
 Black 13.9 ± 0.32 13.9 ± 0.32 9.1 ± 0.28
 Hispanic 9.7 ± 0.31 9.7 ± 0.31 12.9 ± 0.47
 Other 6.1 ± 0.24 6.1 ± 0.24 5.9 ± 0.33
 Unknown 5.2 ± 0.39 5.2 ± 0.39 4.4 ± 0.49
Obesity, % ± se 11.8 ± 0.09 11.6 ± 0.09 36.5 ± 0.45 <0.001c
Smoking, % ± se 24.7 ± 0.20 24.7 ± 0.20 29.3 ± 0.32 <0.001c
Alcohol use, % ± se 3.2 ± 0.05 3.2 ± 0.05 4.8 ± 0.12 <0.001c
Diabetes, % ± se 24.4 ± 0.11 24.3 ± 0.11 42.6 ± 0.28 <0.001c
Hypertension, % ± se 38.8 ± 0.13 38.7 ± 0.13 49.7 ± 0.29 <0.001c
Dyslipidemia, % ± se 24.0 ± 0.16 24.0 ± 0.16 30.9 ± 0.30 <0.001c
Metabolic syndrome, % ± se 0.18 ± 0.01 0.17 ± 0.01 1.3 ± 0.10 <0.001c
HIV, % ± se 0.70 ± 0.02 0.70 ± 0.02 0.84 ± 0.05 0.002c
Cirrhosis, % ± se 1.9 ± 0.02 1.8 ± 0.02 8.2 ± 0.23 <0.001c
HCC, % ± se 0.22 ± 0.01 0.21 ± 0.01 0.50 ± 0.04 <0.001c
OSA, % ± se 4.9 ± 0.05 4.8 ± 0.05 13.6 ± 0.30 <0.001c
HCV, % ± se 2.0 ± 0.03 1.9 ± 0.03 2.5 ± 0.09 <0.001c
HBV, % ± se 0.11 ± 0.004 0.11 ± 0.004 0.16 ± 0.02 0.002c
Hemochromatosis, % ± se 0.06 ± 0.001 0.06 ± 0.001 0.24 ± 0.02 <0.001c
Num. of Elixhauser’s comorbidities, % ± se <0.001c
 0 19.6 ± 0.16 19.7 ± 0.16 0.38 ± 0.03
 1 17.9 ± 0.07 18.0 ± 0.07 6.6 ± 0.15
 2 19.2 ± 0.05 19.2 ± 0.05 14.1 ± 0.20
 3+ 43.3 ± 0.19 43.1 ± 0.19 78.9 ± 0.28
Modified Comorbidity Index1, mean ± se 1.5 ± 0.01 1.5 ± 0.01 1.7 ± 0.01 <0.001a
Modified Comorbidity Index1, % ± se <0.001c
 0 42.7 ± 0.19 42.8 ± 0.19 31.7 ± 0.29
 1 21.5 ± 0.06 21.4 ± 0.06 27.0 ± 0.24
 2 14.1 ± 0.06 14.1 ± 0.06 16.3 ± 0.19
 3+ 21.7 ± 0.13 21.6 ± 0.13 24.9 ± 0.33

Data presented as Weighted Frequency (%) unless otherwise stated.

N are the unweighted frequency and Wgt N are the weighted frequencies

*

Data not available for all subjects. Gender = 429.

P-values: a=linear regression; c=Rao-Scott chi-square test.

SAS Survey Procedures used for all analyses.