Table 2.
Changes in AF, osmolality, composition concentration and foetus, foetal membrane and placenta weights as well as placenta areas among the AQP1 homozygote and wild-type groups at 13.5 GD (mean ± SD)
| Parameters | AQP1+/+ | AQP1−/− |
|---|---|---|
| AF (g) | 135 ± 19.2 (n = 5) | 130 ± 29.1 (n = 5) |
| Osmolality (mOsm/L) | 301 ± 24.7 (n = 5) | 302 ± 29.0 (n = 5) |
| Total protein (g/L) | 3.40 ± 0.990 (n = 5) | 3.62 ± 0.420 (n = 5) |
| Glucose (g/L) | 2.37 ± 0.862 (n = 5) | 3.35 ± 0.861 (n = 5) |
| Urea (mmol/L) | 8.04 ± 1.61 (n = 5) | 7.31 ± 1.92 (n = 5) |
| Creatinine (mmol/L) | 9.83 ± 1.45 (n = 5) | 10.23 ± 3.26 (n = 5) |
| Na+ (mmol/L) | 141 ± 8.34 (n = 5) | 140.5 ± 10.7 (n = 5) |
| K+ (mmol/L) | 6.61 ± 0.792 (n = 5) | 7.58 ± 1.27 (n = 5) |
| Cl− (mmol/L) | 102 ± 8.25 (n = 5) | 105 ± 9.51 (n = 5) |
| Ca2+ (mmol/L) | 1.81 ± 0.641 (n = 5) | 1.93 ± 0.572 (n = 5) |
| Foetus weight (mg) | 140 ± 19.5 (n = 41) | 132 ± 36.8 (n = 37) |
| Foetal membrane weight (mg) | 15.9 ± 3.27 (n = 41) | 16.1 ± 4.33 (n = 37) |
| Placenta weight (mg) | 65.4 ± 10.3 (n = 41) | 74.3 ± 18.0* (n = 37) |
| Placental area (mm2) | 0.453 ± 0.0201 (n = 41) | 0.422 ± 0.0312 (n = 37) |
Data were analysed by ANOVA. *P < 0.05 versus wild type (AQP1+/+group)
GD, gestational day; SD, standard deviation; ANOVA, analysis of variance