Table 3.
Changes in AF, osmolality, composition concentration and foetus, foetal membrane and placenta weights as well as placenta areas among the AQP1 homozygote and wild-type groups at 16.5 GD (mean ± SD)
| Parameters | AQP1+/+ | AQP1−/− |
|---|---|---|
| AF (g) | 183 ± 25.5 (n = 5) | 196 ± 23.3* (n = 5) |
| Osmolality (mOsm/L) | 400 ± 16.5 (n = 5) | 312 ± 6.01* (n = 5) |
| Total protein (g/L) | 2.86 ± 0.412 (n = 5) | 2.69 ± 0.642 (n = 5) |
| Glucose (g/L) | 1.83 ± 0.621 (n = 5) | 1.86 ± 0.761 (n = 5) |
| Urea (mmol/L) | 7.43 ± 1.10 (n = 5) | 7.07 ± 1.17 (n = 5) |
| Creatinine (mmol/L) | 13.0 ± 3.36 (n = 5) | 12.7 ± 5.57 (n = 5) |
| Na+ (mmol/L) | 146 ± 4.28 (n = 5) | 142.4 ± 4.95 (n = 5) |
| K+ (mmol/L) | 7.82 ± 1.84 (n = 5) | 8.18 ± 1.81 (n = 5) |
| Cl− (mmol/L) | 109 ± 6.03 (n = 5) | 108.6 ± 4.70 (n = 5) |
| Ca2+ (mmol/L) | 1.73 ± 0.472 (n = 5) | 1.40 ± 0.361(n = 5) |
| Foetus weight (mg) | 556 ± 121 (n = 42) | 656 ± 115* (n = 40) |
| Foetal membrane weight (mg) | 30.1 ± 7.22 (n = 42) | 31.2 ± 6.58 (n = 40) |
| Placenta weight (mg) | 79.2 ± 11.6 (n = 42) | 79.9 ± 9.91 (n = 40) |
| Placental area (mm2) | 0.412 ± 0.0323 (n = 42) | 0.451 ± 0.0412 (n = 40) |
Data were analysed by ANOVA. *P < 0.05 versus wild type (AQP1+/+group)
GD, gestational day; SD, standard deviation; ANOVA, analysis of variance