Table 2.
Comparison of structural parameters between patients with and without fat metaplasia. PDFF75, PDFF90, etc. refer to the 75th and 90th percentiles of ADC measurements in the defined ROI. Estimates are displayed as mean (95% CI). Odds ratio (OR) and p values (*) were derived from logistic regression. The highest ROC AUC value for the evaluation of fat metaplasia is shown in italics. Sensitivity and specificity values for the optimal cutoff values (far right) are provided in the main “Results” section. The right-hand p values (**) relate to the comparison of ROC AUC with the median value
| Fat metaplasia | ||||||||
|---|---|---|---|---|---|---|---|---|
| Present (n = 30) | Absent (n = 23) | OR (95% CI) | *p= | ROC AUC (95% CI) | Optimal cutoff | **p= | ||
| PDFFmean | 48.2 (43.9–52.5) % | 37.4 (33.7–41.1) % | 1.110 (1.035–1.119) | 0.003 | 0.759 (0.629–0.889) | – | 0.061 | |
| PDFFmedian | 48.2 (44.1–52.3) % | 38.0 (34.0–41.9) % | 1.100 (1.030–1.174) | 0.004 | 0.735 (0.597–0.872) | – | – | |
| PDFF75 | 57.1 (52.0–62.2) % | 44.5 (48.2–40.8) % | 1.105 (1.034–1.182) | 0.003 | 0.759 (0.630–0.888) | – | 0.254 | |
| PDFF90 | 64.3 (59.2–69.4) % | 50.4 (46.5–54.3) % | 1.111 (1.037–1.189) | 0.002 | 0.780 (0.656–0.903) | 55.7% | 0.263 | |
| ADCmean | 606 (541–671) | 652 (571–732) | 0.999 (0.996–1.002) | 0.380 | 0.567 (0.407–0.726) | – | 0.669 | |
| ADCmedian | 602 (535–669) | 648 (572–724) | 0.999 (0.996–1.002) | 0.380 | 0.572 (0.413–0.731) | – | – | |