Table 2.
Optic chiasm measures
| Measure | HC | NMOSD-NON | NMOSD-ON | HC vs. NMOSD-NON | HC vs. NMOSD-ON | NMOSD-NON vs. NMOSD-ON | CoV | ICC |
|---|---|---|---|---|---|---|---|---|
| Left height (CI, mm) |
2.77 (0.35) |
2.34 (0.53) |
1.94 (0.48) |
t = 2.77 p = 0.01 |
t = 7.49 p < 0.0001 |
t = 2.36 p = 0.03 |
0.12 | 0.71 |
| Central height (CI, mm) |
1.93 (0.32) |
1.55 (0.39) |
1.22 (0.32) |
t = 3.27 p < 0.001 |
t = 8.63 p < 0.0001 |
t = 2.70 p = 0.013 |
0.16 | 0.51 |
| Right height (CI, mm) |
2.65 (0.36) |
2.20 (0.46) |
1.79 (0.43) |
t = 3.31 p = 0.003 |
t = 8.23 p < 0.0001 |
t = 2.79 p = 0.008 |
0.14 | 0.77 |
| Width (CI, mm) |
12.23 (1.15) |
12.17 (1.05) |
11.43 (1.87) |
t = 0.17 p = 0.56 |
t = 1.91 p = 0.059 |
t = 1.59 p = 0.18 |
0.09 | 0.95 |
| Area (CI, mm2) |
27.07 (3.50) |
22.26 (4.65) |
16.89 (4.44) |
t = 3.51 p = 0.003 |
t = 9.61 p < 0.0001 |
t = 3.51 p = 0.001 |
0.13 | 0.89 |
| Total height (CI, mm) |
7.35 (0.90) |
6.09 (1.33) |
4.94 (1.14) |
t = 3.27 p = 0.003 |
t = 8.86 p < 0.0001 |
t = 2.73 p = 0.009 |
0.12 | 0.76 |
Shown are means of OC measures. p and t-values are derived from t tests. Corrected p = 0.003. CI = 95% confidence interval; HC = healthy controls; NMOSD-ON = neuromyelitis optica patients with history of optic neuritis; NMOSD-NON = neuromyelitis optica patients without history of optic neuritis; CoV = coefficient of variation; ICC = intraclass correlations