Table 3.
Receiver operating characteristics analysis
| HC vs. NMOSD-ON | Area | Width |
Left Height |
Central Height |
Right Height |
Total Height |
| AUC | 0.95 | 0.64 | 0.90 | 0.95 | 0.92 | 0.94 |
| 95% CI | 0.91–1.00 | 0.49–0.79 | 0.81–0.98 | 0.89–1.00 | 0.85–1.00 | 0.87–1.00 |
| p value AUC comparison | – | < 0.01 | 0.02 | 0.78 | 0.16 | 0.40 |
| HC vs. NMOSD-NON | Area | Width |
Left Height |
Central Height |
Right Height |
Total Height |
| AUC | 0.78 | 0.55 | 0.74 | 0.80 | 0.78 | 0.77 |
| 95% CI | 0.57–0.92 | 0.38–0.73 | 0.52–0.88 | 0.59–0.95 | 0.62–0.94 | 0.60–0.94 |
| p value AUC comparison | – | 0.08 | 0.31 | 0.49 | 0.93 | 0.77 |
| NMOSD-ON vs. NMOSD-NON | Area | Width |
Left Height |
Central Height |
Right Height |
Total Height |
| AUC | 0.81 | 0.63 | 0.71 | 0.74 | 0.76 | 0.76 |
| 95% CI | 0.69–0.95 | 0.46–0.80 | 0.54–0.89 | 0.59–0.90 | 0.57–0.90 | 0.60–0.92 |
| p value AUC comparison | – | 0.08 | 0.06 | 0.19 | 0.29 | 0.14 |
Shown are area under the curve (AUC), 95% confidence interval (CI), and p value for AUC comparison using area as reference. HC = healthy controls; NMOSD-ON = neuromyelitis optica patients with history of optic neuritis; NMOSD-NON = neuromyelitis optica patients without history of optic neuritis