Table 1.
Commercially-available tests for BV, with diagnostic capability and markers of detection.
| Test and manufacturer | Quantitative or qualitative | BV markers |
|---|---|---|
| NuSwab® (LabCorp, Burlington, NC) | Semi-quantitative; Qualitative | Atopobium vaginae, BVAB2, Megasphaera-1, L. crispatus (Cartwright et al., 2012) |
| SureSwab® real-time PCR assay (Quest diagnostics, Secaucus, NJ) | Quantitative; Qualitative | Lactobacillus spp., Atopobium vaginae, Megasphaera spp., Gardnerella vaginalis |
| BD MAX™ real-time PCR assay (Becton, Dickinson and company, Franklin Lakes, NJ) | Quantitative; Qualitative | BV Candida group (C. albicans, C. tropicalis, C. parapsilosis, and C. dubliniensis), C. glabrata or C. krusei, and Trichomonas vaginalis, Lactobacillus spp. (L. crispatus, L. jensenii, Atopobium vaginae, Megasphaera spp., Gardnerella vaginalis, BVAB2 (Gaydos et al., 2017) |
| BV multiplex assay (Medical Diagnostic Laboratories, Hamilton Township, NJ) | Quantitative; Qualitative | Lactobacillus profiling Atopobium vaginae, Megasphaera phylotypes 1 and 2, Gardnerella vaginalis, BVAB2 (Hilbert et al., 2016) |
| OSOM® BVBlue® assay (Gryphus Diagnostics, LLC, Knoxville, TN) | Qualitative | Sialidase enzyme activity (Myziuk et al., 2003) |
| FemExam® card (Litmus Concepts, Santa Clara, CA) | Qualitative | Vaginal pH and amine activity (West et al., 2003) |
| IMMULITE® immunoassay (Siemens Healthcare, Erlangen, Germany) | Quantitative; Qualitative | Levels of cytokines: TNF-α, IL-6, IP-10 (Zirath et al., 2017) |
| QuickLine immunoassay (Milenia Biotec, Gießen, Germany) | Quantitative; Qualitative | Levels of cytokines: IL-6, TNF-α (Kunze et al., 2016) |