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. 2020 Aug 17;10:13908. doi: 10.1038/s41598-020-70483-3

Table 2.

Results from fixed effects models showing the relationship between isolation, loneliness and physical performance: all predictors entered simultaneously.

Total physical performance 5 times sit-to-stand Balance Walking speed
Coef (95% CI) p Coef (95% CI) p Coef (95% CI) p Coef (95% CI) p
Domestic isolation
Model 1 − 1.454 (− 1.71 to − 1.37) < 0.001 − 0.47 (− 0.56 to − 0.39) < 0.001 − 0.49 (− 0.56 to − 0.43) < 0.001 − 0.57 (− 0.64 to − 0.50) < 0.001
Model 2 − 0.36 (− 0.50 to − 0.21) < 0.001 − 0.05 (− 0.13 to 0.02) 0.16 − 0.15 (− 0.21 to − 0.08) < 0.001 − 0.16 (− 0.22 to − 0.09) < 0.001
Model 3 − 0.34 (− 0.48 to − 0.21) < 0.001 − 0.05 (− 0.13 to 0.02) 0.15 − 0.14 (− 0.20 to − 0.08) < 0.001 − 0.15 (− 0.21 to − 0.09) < 0.001
Model 4 − 0.32 (− 0.46 to − 0.19) < 0.001 − 0.05 (− 0.12 to 0.03) 0.20 − 0.14 (− 0.20 to − 0.07) < 0.001 − 0.14 (− 0.20 to − 0.08) < 0.001
Low social contact
Model 1 0.009 (− 0.04 to 0.02) 0.54 − 0.007 (− 0.02 to 0.01) 0.39 − 0.004 (− 0.01 to 0.01) 0.47 0.002 (− 0.01 to 0.02) 0.81
Model 2 0.004 (− 0.03 to 0.02) 0.77 − 0.005 (− 0.02 to 0.01) 0.49 − 0.001 (− 0.01 to 0.01) 0.80 0.002 (− 0.01 to − 0.02) 0.69
Model 3 0.002 (− 0.02 to 0.03) 0.90 − 0.004 (− 0.02 to 0.01) 0.55 0.001 (− 0.01 to 0.01) 0.88 0.005 (− 0.007 to 0.02) 0.39
Model 4 0.001 (− 0.02 to 0.03) 0.94 − 0.005 (− 0.02 to 0.01) 0.53 0.001 (− 0.01 to 0.01) 0.90 0.005 (− 0.007 to 0.02) 0.42
Social disengagement
Model 1 − 0.27 (− 0.30 to − 0.23) < 0.001 − 0.08 (− 0.09 to − 0.06) < 0.001 − 0.08 (− 0.10 to − 0.07) < 0.001 − 0.11 (− 0.12 to − 0.09) < 0.001
Model 2 − 0.14 (− 0.17 to − 0.11) < 0.001 − 0.03 (− 0.05 to − 0.02) < 0.001 − 0.05 (− 0.06 to − 0.03) < 0.001 − 0.06 (− 0.08 to − 0.05) < 0.001
Model 3 − 0.10 (− 0.13 to − 0.07) < 0.001 − 0.02 (− 0.04 to − 0.01) 0.003 − 0.03 (− 0.05 to − 0.02) < 0.001 − 0.04 (− 0.06 to − 0.03) < 0.001
Model 4 − 0.10 (− 0.12 to − 0.07) < 0.001 − 0.02 (− 0.04 to − 0.01) 0.004 − 0.03 (− 0.05 to − 0.02) < 0.001 − 0.04 (− 0.06 to − 0.03) < 0.001
Loneliness
Model 1 − 0.16 (− 0.20 to − 0.12) < 0.001 − 0.06 (− 0.08 to − 0.04) < 0.001 − 0.03 (− 0.05 to − 0.02) < 0.001 − 0.07 (− 0.09 to − 0.05) < 0.001
Model 2 − 0.14 (− 0.17 to − 0.11) < 0.001 − 0.05 (− 0.07 to − 0.03) < 0.001 − 0.03 (− 0.04 to − 0.02) < 0.001 − 0.06 (− 0.07 to − 0.05) < 0.001
Model 3 − 0.09 (− 0.12 to − 0.06) < 0.001 − 0.03 (− 0.05 to − 0.02) < 0.001 − 0.02 (− 0.03 to − 0.002) 0.02 − 0.04 (− 0.05 to − 0.02) < 0.001
Model 4 − 0.06 (− 0.09 to − 0.02) 0.001 − 0.03 (− 0.04 to − 0.01) 0.002 − 0.01 (− 0.02 to 0.01) 0.23 − 0.02 (− 0.03 to − 0.01) 0.002

N = 8,780, 3 observations per person, total observations 26,340. Model 1: accounting for all time-invariant factors and time. Model 2: additionally adjusted for time-varying demographic factors (age, marital status, employment status and wealth). Model 3: additionally adjusted for time-varying health factors (BMI, eyesight, comorbidities, chronic pain, frequency of alcohol consumption, smoking habits, inactivity and cognition). Model 4: additionally adjusted for time-varying mental health (depression).