Table 3.
Results of replication studies in the 1Mv3 data set for statistically significant chromosomal loci in the discovery studies.
Cluster no. | ID | Chr | hg19 | Minor/major | MAF (%) | OR | 95% CI | P | GENESYMBOL | Function |
---|---|---|---|---|---|---|---|---|---|---|
5 | rs13332627 | 16 | 22,874,928 | G/A | 10.0 | 0.50 | 0.18–1.45 | 0.195 | ||
5 | rs7199670 | 16 | 22,875,238 | A/G | 12.2 | 0.51 | 0.20–1.33 | 0.1629 | HS3ST2 | Intronic |
5 | rs1054028 | 16 | 22,927,214 | G/A | 15.0 | 0.51 | 0.22–1.21 | 0.121 | HS3ST2 | UTR3 |
10 | rs1876769 | 2 | 22,678,191 | A/G | 1.4 | NA | – | 0.1822 | LINC01822, LINC01884 | Intergenic |
13 | rs11064685 | 12 | 119,590,881 | G/A | 8.2 | 1.89 | 1.06–3.37 | 0.02858 | SRRM4 | Intronic |
14 | rs7189512 | 16 | 66,324,048 | A/G | 3.5 | 2.16 | 0.83–5.67 | 0.1085 | LINC00922, CDH5 | Intergenic |
15 | rs276833 | 2 | 114,769,078 | A/G | 1.3 | 0.71 | 0.09–5.75 | 0.75 | LINC01191, DPP10 | Intergenic |
Chr chromosome, OR odds ratio, CI confidence interval.