Table 2.
n (%) | Events (n) | Incidence ratea | Model 1 | Model 2 | |
---|---|---|---|---|---|
Smoking status | |||||
Nonsmoker | 300,126 (92.3) | 1,795 | 6.0 | 1 (ref.) | 1 (ref.) |
Former smoker | 12,174 (3.7) | 143 | 11.7 | 1.83 (1.54, 2.18) | 1.55 (1.27, 1.90) |
Current smoker | 12,997 (4.0) | 176 | 13.5 | 2.36 (2.01, 2.77) | 1.73 (1.42, 2.09) |
Amount of smoking (no. of cigarettes smoked per day) | |||||
Nonsmoker | 300,126 (92.3) | 1,795 | 6.0 | 1 (ref.) | 1 (ref.) |
Former smoker | |||||
< 15 | 11,454 (3.5) | 127 | 11.1 | 1.75 (1.46, 2.11) | 1.49 (1.21, 1.84) |
≥ 15 | 720 (0.2) | 16 | 22.2 | 2.93 (1.77, 4.85) | 2.42 (1.36, 4.31) |
Current smoker | |||||
< 15 | 11,736 (3.6) | 150 | 12.8 | 2.26 (1.90, 2.68) | 1.65 (1.35, 2.03) |
≥ 15 | 1,261 (0.4) | 26 | 20.6 | 3.27 (2.19, 4.88) | 2.35 (1.46, 3.79) |
Duration of smoking (years) | |||||
Nonsmoker | 300,268 (92.3) | 1,797 | 6.0 | 1 (ref.) | 1 (ref.) |
Former smoker | |||||
< 5 | 4,816 (1.5) | 50 | 10.4 | 1.93 (1.45, 2.56) | 1.60 (1.14, 2.23) |
≥ 5 | 7,265 (2.2) | 92 | 12.7 | 1.78 (1.43, 2.21) | 1.53 (1.20, 1.95) |
Current smoker | |||||
< 5 | 2,347 (0.7) | 19 | 8.1 | 1.84 (1.16, 2.90) | 1.38 (0.82, 2.30) |
≥ 5 | 10,601 (3.3) | 156 | 14.7 | 2.43 (2.05, 2.89) | 1.78 (1.45, 2.19) |
Amount × duration of smoking (pack-years) | |||||
Nonsmoker | 300,126 (92.3) | 1,795 | 6.0 | 1 (ref.) | 1 (ref.) |
≤ 2 | 13,625 (4.2) | 139 | 10.2 | 1.86 (1.56, 2.21) | 1.50 (1.22, 1.84) |
2 <, ≤ 4 | 6,210 (1.9) | 81 | 13.0 | 2.21 (1.76, 2.77) | 1.71 (1.31, 2.22) |
4 <, ≤ 6 | 3,222 (2.0) | 49 | 15.2 | 2.23 (1.67, 2.98) | 1.60 (1.13, 2.26) |
6 <, ≤ 8 | 1,085 (0.3) | 18 | 16.6 | 2.20 (1.37, 3.53) | 1.97 (1.14, 3.40) |
8 <, ≤ 10 | 568 (0.2) | 16 | 28.2 | 2.97 (1.76, 5.00) | 2.34 (1.22, 4.51) |
> 10 | 461 (0.1) | 16 | 34.7 | 3.27 (1.96, 5.45) | 2.29 (1.25, 4.22) |
Model 1: Adjusted for age, alcohol drinking, regular exercise, and income status.
Model 2: Adjusted for model 1 + body mass index, fasting blood glucose, family history of diabetes, and dyslipidemia.
aPer 1,000 person-years.