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. 2020 Aug 11;11:1699. doi: 10.3389/fimmu.2020.01699

Figure 2.

Figure 2

Lower levels of salivary flow rate and CD4+IL-10+ T cells in Il-27−/−NOD mice. (A) Histological analysis, SG from representative 12-week-old female NOD and Il-27−/−NOD and IL-27–treated Il-27−/−NOD mice stained with hematoxylin and eosin to assess inflammation (top, magnification ×100; bottom, magnification ×400). (B) The lymphocyte infiltration in SG of mice were evaluated for histological scores. (C) Salivary flow rate, (D) representative flow cytometry results, and (E) the percentage and (F) absolute number of splenic CD4+IL-10+ T cells in NOD and Il-27−/−NOD and IL-27–treated Il-27−/−NOD mice. Error bars indicate SEM. *p < 0.05, **p < 0.01, ***p < 0.001, n = 5.