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CD4+IL-10+ T cells generation and differentiation were promoted by IL-27. (A) IL-27 treatment schedule. (B) Representative flow cytometry results and (C) the percentage of splenic CD4+IL-10+ T cells in IL-27–treated or control OVA-immunized 9-week-old female C57BL/6 mice. (D) Representative flow cytometry results, and (E) the percentage of differentiated CD4+IL-10+ T cells. Error bars indicate SEM. *p < 0.05, **p < 0.01, n = 5.
