Table 1.
CAR staining reagents.
| Property | Anti-IgG antibodies | Protein L | Antigen-Fc | Anti-idiotype antibody | Anti-linker antibody |
|---|---|---|---|---|---|
| One-step staining | Yes | No | No | Yes | Yes |
| Compatibility w/antibody panels | Inconsistent | No | Yes | Yes | Yes |
| Compatibility w/FcX reagents | Inconsistent | No | Some | Yes | Yes |
| Reagent stability | High | High | Often low | High | High |
| Specificity for CAR | Low | Low | High | High | High |
| Access to academic labs | Easy | Easy | Easy | Hard | Hard |