Table 1.
Anthropometric and medical characteristics of the participants (n = 40).
| Characteristics | N (%) | Mean ± SD | Median | Range |
|---|---|---|---|---|
| Age at diagnosis (years) | 40 (100) | 8.26 ± 4.32 | 9 | 0–16 |
| Age at assessment (years) | 40 (100) | 11.28 ± 3.80 | 11.0 | 6–18 |
| <8 years | 10 (25) | |||
| ≥8 years | 30 (75) | |||
| Period post-diagnosis (years) | 40 (100) | 2.81 ± 3.17 | 1.6 | 0.2–14 |
| Period post-treatment (years) | 40 (100) | 1.56 ± 1.79 | 1.04 | 0.2–10.33 |
| <1 year | 19 (48) | |||
| 1–5 years | 20 (50) | |||
| >5 years | 1 (3) | |||
| Leukemia/Lymphoma | 18 (45) | |||
| Bone tumor | 2 (5) | |||
| Brain tumor | 7 (18) | |||
| Other solid tumors* | 13 (33) | |||
| Body mass index• (kg/m2) | 40 (100) | 17.63 ± 3.26 | 16.80 | 12.2–27.50 |
| Underweight | 9 (23) | |||
| Normal weight | 25 (63) | |||
| Overweight | 6 (15) | |||
| Chemotherapy | 27 (68) | |||
| Anthracycline application | 25 (63) | |||
| Cumulative dose (mg/m2) | 207 ± 81 | 227 | 92–354 | |
| Radiotherapy | 13 (33) | |||
| Chest-directed radiation | 4 (10) | |||
| Anthracycline + chest radiation | 4 (10) | |||
| Surgical tumor resection | 19 (48) | |||
| Relapse | 12 (30) |
Results are given in Mean ± SD (M, median; Range).
*
Other solid tumors: alveolar rhabdomyosarcoma (n = 1), carcinoid tumor of the appendix (n = 2), nephroblastoma (n = 3), focal nodular hyperplasia liver (n = 1), mature cystic teratoma ovary (n = 2), thoracic ganglioneuroma (n = 2), papillary thyroid carcinoma (n = 1), neuroblastoma (n = 2).
•
BMI was converted into percentiles and classified in underweight <10th percentile, normal weight 10th−90th percentile and overweight >90th percentile (26).
Thirteen participants received a combination of anthracyclines (mainly the combination of Doxorubicin and Daunorubicin).