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. 2020 Aug 11;11:922. doi: 10.3389/fgene.2020.00922

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Copyright © 2020 Khezri, Narud, Stenseth, Zeremichael, Myromslien, Wilson, Ahmad and Kommisrud.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Numbers and levels of significant DMRs identified in the sperm DNA methylome between identical 14 months old bulls (test) and 17 months old bulls (control). (A) Total number of significant DMRs indicating that 60% are hypomethylated in the test group compared to the control group. (B,C) Different levels of hypo- and hypermethylated regions in the test group compared to the control group. Explanation of percentage ranges: DMRs_<_10% indicating regions with less than 10% difference in DNA methylation, DMRs₁₀_–_25% indicating regions having between 10 and 25% difference in DNA methylation, DMRs_>_25% indicating regions having over 25% difference in DNA methylation.