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. 2020 Aug 11;11:922. doi: 10.3389/fgene.2020.00922

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Copyright © 2020 Khezri, Narud, Stenseth, Zeremichael, Myromslien, Wilson, Ahmad and Kommisrud.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Annotation of the filtered DMRs with varying degrees of methylation difference to the nearest TSSs. Numbers inside the circles, showing the number of closest unique TSSs (duplicated TSSs removed) to DMRs in (A) hypomethylation and (B) hypermethylation groups. Explanation of percentage ranges: DMRs_<_10% indicating regions with less than 10% difference in DNA methylation, DMRs₁₀_–_25% indicating regions having between 10 and 25% difference in DNA methylation, DMRs_>_25% indicating regions having over 25% difference in DNA methylation.