FIGURE 1.

Cec4 inhibits clinical resistant bacteria and biofilms. (A) Distribution of MIC value of Cec4 against 200 CRAB clinical isolates (μg/mL). (B) Quantification of biofilm formation in 200 CRAB clinical isolates. A. baumannii ATCC19606 was used as a positive control. Experiments were performed in triplicate and each bar represents the mean ± standard deviation. (C) The effects of Cec4 on mature biofilms of CRAB. The adherent biofilm was stained by crystal violet, and then the dye was extracted with ethanol, measured at a 570-nm absorbance, and presented as percentage of biofilm remains compared to untreated wells (0 μg/mL). All experiments were done in triplicate for statistical significance. *p < 0.05; **p < 0.01.