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. 2020 Aug 11;14:139. doi: 10.3389/fnbeh.2020.00139

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Copyright © 2020 Jarrin, Pandit, Roche and Finn.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of optogenetic stimulation (ChR2) or inhibition (ArchT) of glutamatergic neurons in the ACC on c-Fos positive cells in the ACC of SD rats. (A) Representative images of c-Fos (green) expression within the ACC (scale bar = 200 μm). White arrows denote representative c-Fos-positive staining. (B) Effects of optogenetic stimulation (ChR2) or inhibition (ArchT) of glutamatergic neurons in the ACC on c-Fos positive cells in the ACC of male SD rats. Data are mean ± SEM (n = 5–6 per group). *p < 0.05 vs. control. (C) Effects of optogenetic stimulation (ChR2) or inhibition (ArchT) of glutamatergic neurons in the ACC on percent of c-Fos positive cells in the ACC of female SD rats. Data are mean ± SEM (n = 4–6 per group). *p < 0.05 vs. control.