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. 2020 Aug 11;8:704. doi: 10.3389/fcell.2020.00704

FIGURE 7.

FIGURE 7

Schematic representation of the proposed PI3K/Akt signaling-induced cell cycle arrest and apoptosis triggered by Fufang Yiliu Yin (FYY). By combining the network pharmacological analysis and our results, we hypothesized that FYY activates the PI3K/Akt signaling pathway and modulates the expression of P21, C-MYC, and BCL-2 family proteins, thereby inducing cell cycle arrest and apoptosis.