Table 2.

Prognostic value of the microRNAs expression profile mentioned in the literature.

microRNA	HR (95% CI)	Heterogeneity test		Sample size	Expression	Outcome	Number of microRNA
		I2 (%)	Chi2 (P)
miR-133b	5.53 (2.58–11.83)	0.0%	0.939	100	Low expression	OS/DFS	2
miR-206	5.66 (2.69–11.88)	0.0%	0.914	100	Low expression	OS/DFS	2
miR-133b/206	9.48 (4.59–19.57)	0.0%	0.953	100	Low expression	OS/DFS	2
miR-195	4.23 (2.31–7.73)	0.0%	0.568	166	Low expression	OS/DFS	2
miR-152	0.13 (0.02–0.70)	–	–	80	Low expression	OS	1
miR-223	4.59 (1.84–11.45)	–	–	112	Low expression	OS	1
miR-326	3.90 (1.13–12.53)	–	–	60	Low expression	OS	1
miR-95-3p	4.22 (2.31–8.07)	–	–	133	Low expression	OS	1
miR-497	3.96 (2.39–6.58)	0.0%	0.868	185	Low expression	OS	2
miR-491	3.06 (1.56–6.00)	0.0%	0.928	102	Low expression	OS	2
miR-124	3.73 (2.27–6.12)	0.0%	0.841	114	Low expression	OS/DFS	2
miR-491-5p	2.68 (1.66–4.32)	0.0%	0.951	72	Low expression	DFS/OS	2
miR-101	4.16 (2.80–6.19)	0.0%	0.995	152	Low expression	OS/RFS	4
miR-139-5p	3.03 (2.17–4.23)	0.0%	0.707	98	Low expression	OS	2
miR-29a	5.68 (2.50–12.92)	0.0%	0.903	80	High expression	OS/DFS	2
miR-29b	5.71 (2.58–12.67)	0.0%	0.904	80	High expression	OS/DFS	2
miR-196a	6.59 (3.08–14.11)	0.0%	0.896	100	High expression	OS/DFS	2
miR-196b	6.64 (3.09–14.24)	0.0%	0.900	100	High expression	OS/DFS	2
miR-196a/196b	9.99 (4.82–20.69)	0.0%	0.979	100	High expression	OS/DFS	2
miR-221	7.26 (3.29–16.04)	0.0%	0.886	108	High expression	RFS/OS	2
miR-27a	3.36 (1.90–5.95)	0.0%	0.851	166	High expression	OS/DFS	2
miR-191	3.05 (1.75–5.31)	0.0%	0.593	100	High expression	OS/DFS	2
miR-300	5.07 (3.41–7.54)	0.0%	0.958	114	High expression	OS/DFS	4
miR-542-3p	7.83 (5.41–11.34)	0.0%	0.431	76	High expression	OS/PFS	4
miR-194	4.01 (2.53–6.36)	0.0%	0.695	124	Low expression	OS/DFS	2

DFS, Disease-free survival; OS, Overall survival; RFS, Recurrence-free survival; PFS, Progression-free survival; –, Not available.