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. 2020 Aug 11;8:943. doi: 10.3389/fbioe.2020.00943

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Copyright © 2020 Yaman, Ramachandramoorthy, Oter, Zhukova, Nguyen, Sabnani, Weidanz and Nguyen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cyto-/Hemo-compatibility of T-MNPs. (A) Cyto-compatibility of T-MNPs was analyzed on human dermal fibroblasts (HDFs) at varying NPs concentrations (50—1,000 μg/ml) for 24 h, and cell viability was quantified using MTS assays (n = 3). (B) Blood clotting kinetics of T-MNPs. Clotting efficiency was measured in absorbance units (OD) of the supernatants collected from T-MNPs treated blood samples at pre-determined time-points: 10, 20, 30, and 60 min. The absorbances were quantified using a UV-vis Spectrophotometer (n = 9).