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. 2020 Aug 11;8:758. doi: 10.3389/fcell.2020.00758

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Copyright © 2020 Yang, Yang, Yang, Zhao and Wei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Tumor microenvironment related therapeutic strategies in ovarian cancer. The graph shows multiple strategies targeted the tumor microenvironment in ovarian cancer. Among them, several strategies are currently in clinical use, while others are at different phases of clinical development. CAFs: Cancer-associated fibroblasts; TGF-β: Transforming growth factor-β; TAMs: Tumor-associated macrophages; CCL2: chemokine (C-C motif) ligand 2; CSF-1R: colony stimulating factor-1 (CSF1) receptor; VEGF: Vascular endothelial growth factors; VEGFR: Vascular endothelial growth factor receptor.