Table 2.
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Groups | ||||||||
Parameters | Level | Total ( n = 612) | RP ( n = 264) | Stargardt ( n = 76) | Cone- Rod Dystrophy (n = 109) | Usher Syndrome ( n = 54) | Control ( n = 109) | P -value |
BCVA (LogMAR) | Mean SD | 1.04 0.91 | 1.19 0.98 | 1.02 0.47 | 1.43 0.87 | 0.84 0.69 | 0 0 | 0.001 |
Median (range) | 0.8 (0 to 2.79) | 0.8 (0 to 2.79) | 0.9 (0.1 to 2.31) | 1.31 (0 to 2.7) | 0.74 (0.1 to 2.7) | 0 (0 to 0) | ||
SE (D) | Mean SD | –1.0 1.78 | –0.88 1.79 | –1.54 1.33 | –0.88 2.07 | –1.67 1.94 | –0.33 0.94 | 0.001 |
Median (range) | –0.75 (–6.63 to 2.75) | –0.5 (–5.75 to 2.75) | –1.25 (–5.25 to 0.75) | –0.31 (–6.63 to 2.63) | –1.5 (–5.75 to 1.5) | –0.38 (–2 to 2) | ||
CMT (µm) | Mean SD | 215.99 72.1 | 230.66 68.81 | 165.54 65.04 | 186.03 48.59 | 244.88 99.87 | 258.72 15.71 | 0.001 |
Median (range) | 213 (80 to 690) | 222 (95 to 674) | 141 (80 to 378) | 186.5 (88 to 317) | 229.5 (90 to 690) | 259.5 (220 to 285) | ||
Color Vision | Normal | 164 (28.1%) | 40 (16.1%) | 6 (8.3%) | 2 (1.9%) | 7 (14.6%) | 109 (100.0%) | 0.001 |
CVD | 213 (36.5%) | 71 (28.6%) | 53 (73.6%) | 62 (57.9%) | 27 (56.3%) | 0 (0.0%) | ||
N/A | 207 (35.4%) | 137 (55.2%) | 13 (18.1%) | 43 (40.2%) | 14 (29.2%) | 0 (0.0%) | ||
Cataract Type (%) | No | 376 (62.0%) | 101 (38.5%) | 69 (95.8%) | 80 (73.4%) | 17 (31.5%) | 109 (100.0%) | |
CC | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0.001 | |
NS | 44 (7.3%) | 29 (11.1%) | 0 (0.0%) | 11 (10.1%) | 4 (7.4%) | 0 (0.0%) | ||
PSC | 169 (27.9%) | 120 (45.8%) | 3 (4.2%) | 16 (14.7%) | 30 (55.6%) | 0 (0.0%) | ||
PCIOL | 14 (2.3%) | 12 (4.6%) | 0 (0.0%) | 2 (1.8%) | 0 (0.0%) | 0 (0.0%) | ||
Posterior Polar | 3 (0.5%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 3 (5.6%) | 0 (0.0%) | ||
Optic Atrophy (%) | No | 46 (9.1%) | 10 (3.8%) | 22 (28.9%) | 14 (12.8%) | 0 (0.0%) | 0 (0.0%) | 0.001 |
Yes | 457 (90.9%) | 254 (96.2%) | 54 (71.1%) | 95 (87.2%) | 54 (100.0%) | 0 (0.0%) | ||
Macular Involvement (%) | No | 122 (19.9%) | 11 (4.2%) | 0 (0.0%) | 2 (1.8%) | 0 (0.0%) | 109 (100.0%) | 0.001 |
Yes | 490 (80.1%) | 253 (95.8%) | 76 (100.0%) | 107 (98.2%) | 54 (100.0%) | 0 (0.0%) | ||
RP, retinitis pigmentosa; BCVA, best corrected visual acuity; LogMAR, logarithm minimum angle of resolution; SE, spherical equivalent; D, diopter; CMT, central macular thickness; µm, micrometer; CVD, color vision defect; N/A, not applicable; CC, cortical cataract; NS, nuclear sclerotic; PSC, posterior subcapsular; SD, standard deviation; n, number *These parameters are presented based on monocular findings |