Table 10.

Studies on the use of botulinum toxin in PLP.

References	Study type	Blinding	Comparator	Pts n°	Injection route/site	Toxin type*	Dose (U)	Major findings	AEs
(90)	Case report	na	na	1	IM	Onabotulinum toxin type A-Botox®	100 (4 injections performed every 3 months)	Almost complete pain-freedom	-
(89)	RCT	d	Lidocaine/Depomedrol	14	IM/cutaneous/SC	Onabotulinum toxin type A-Botox®	50 for sides	Not superior to placebo	-

PLP, Phantom Limb Pain; RCT, randomized controlled trials; d, double; na, not applicable; *term as originally reported in the study; IM, intramuscular; SC, subcutaneous; U, units; -, not reported.