Table 5.

Studies on the use of botulinum toxin in Occipital Neuralgia.

References	Study type	Blinding	Comparator	Pts n°	Injection route/site	Toxin type*	Dose (U)	Major findings	AEs
(70)	Cases series	na	na	6	Occipital nerve block	Onabotulinum toxin type A-Botox®	100 (50 for each block)	Significant reduction in pain VAS scores and improvement in PDI	-
(71)	PS	s	na	6	Occipital nerve block	Onabotulinum toxin type A-Botox®	100 for each block	Improvement in the sharp/shooting type of pain most commonly associated with occipital neuralgia	-

PS, prospective study; s, single; na, not applicable; ID, intradermal; *term as originally reported in the study; U, units; VAS, visual analog scale; PDI, pain disability index; -, not reported.