FIG 1.
I/LnJ BMDMs resist MNV infection. (A to C) Analysis of replication kinetics of MNV (A), EMCV (B), and MHV-68 (C) in C57BL/6J and I/LnJ BMDMs. Cells were inoculated at a multiplicity of infection (MOI) of 0.05 TCID50/cell and harvested at the indicated time points to determine the titers infectious viruses via TCID50 assay in BV2 cells. All experiments were done in triplicates, and data are presented as mean ± standard error of the mean (SEM). (D) Analysis of MNV replication at 24 h postinfection in C57BL/6J and I/LnJ BMDMs after inoculation at MOIs of 0.05 and 5 TCID50/cell. The experiment was done twice, and data are presented as dots with mean as a bar. N.D., not detected.