TABLE 2.

X-ray data processing and refinement statistics

Parameter	Value for:a
	RLA-A1/VP 60-1	RLA-A1/VP 60-2	RLA-A1/VP 60-10
PDB accession no.	6M2J	6M24	6M2K
Data processing
Space group	P212121	P212121	P212121
Cell dimensions
a, b, c (Å)	49.63, 74.36, 155.67	49.58, 76.22, 155.08	49.61, 74.30, 152.19
α, β, γ (˚)	90.00, 90.00, 90.00	90.00, 90.00, 90.00	90.00, 90.00, 90.00
Wavelength (Å)	0.97911	1.03853	1.03923
Resolution (Å)	50.0–2.2 (2.28-2.2)	50.0–2.3 (2.38–2.3)	50.0–2.6 (2.69–2.6)
Total no. of reflections	276,797	346,034	214,930
No. of unique reflections	29,903	27,014	18,060
Completeness (%)	99.7 (98.8)	99.9 (100.0)	99.9 (100.0)
Redundancy	7.3 (9.3)	12.2 (12.8)	11.9 (12.2)
Rmerge (%)b	17.4 (95.5)	10.1 (85.7)	11.2 (75.8)
I/σ	2.41	2.75	2.78
Refinement
Rwork (%)c	20.2	19.4	21.5
Rfree (%)	25.6	24.6	29.4
RMSD
Bond length (Å)	0.009	0.008	0.009
Bond angle (˚)	1.250	1.200	1.270
Avg B factor (Å2)	38.27	36.77	40.34
Ramachandran plot quality (%)
Favored (%)	97.88	97.88	95.23
Allowed (%)	2.12	2.12	4.77
Outliers (%)	0.00	0.00	0.00

^aNumbers in parentheses represent the highest-resolution shell.

^b$R_{\text{merge}}=\mathrm{\Sigma }h\mathit{kl}\mathrm{\Sigma }i\left|I_i-I\right|{{\displaystyle \mathrm{\Sigma }}}^{}h\mathit{kl}\mathrm{\Sigma }i{I}_i$, where I_i refers to the observed intensity and is the average intensity of multiple observations of symmetry related reflections.

^c$R=\mathrm{\Sigma }h\mathit{kl}\left||F_{\text{obs}}|-k\left|F_{\text{cal}}\right|\right|/\mathrm{\Sigma }h\mathit{kl}\left|F_{\text{obs}}\right|$, where R_free is calculated for a randomly chosen 5% of reflections, and R_work is calculated for the remaining 95% of reflections used for structure refinement.