Table 1.

Drugs with black box warnings for hepatotoxicity [1]

Drug	Dose (mg/day)	Reactive products
Acitretin	25–50	No
Bosentau	125–250	No
Dacarbazine	140–315	Yes
Dantrolene	300–400	Yes
Felbamate	1200	Yes
Flutamide	750	Yes
Gemtuzumab	(9 mg m−3)	Yes
Isoniazid	300	Yes
Ketoconazole	200	Yes
Naltrexone	50	No
Nevirapine	200	Yes
Tolcapone	300	Yes
Trovafloxacin	100–500	No
Valproic acid	1000–2400	Yes
		10/14 = 71%