Table 2.
Data is shown as mean (standard deviation) unless otherwise specified. Raw values are presented for transparency purposes.
| Demographics | AD/MCI | ALS | FTD | PD | CVD |
|---|---|---|---|---|---|
| Number of participants | 126 | 40 | 52 | 140 | 155 |
| Age, years | 71.0 (8.2) | 62.0 (8.7) | 67.8 (7.1) | 67.9 (6.3) | 69.3 (7.4) |
| Sex, n (%) female | 57 (45.2) | 16 (40.0) | 19 (36.5) | 31 (22.1) | 48 (31.0) |
| ST-TIV, cc | 1235.6 (144.6) | 1203.6 (162.8) | 1245.8 (129.6) | 1316.6 (127.0) | 1224.5 (133.2) |
| NAWM, cc | 395.4 (344.5) | 425.0 (78.8) | 295.1 (59.4) | 446.1 (61.2) | 387.4 (54.4) |
| NAGM, cc | 533.3 (51.4) | 556.2 (65.7) | 252.5 (56.0) | 574.7 (47.1) | 535.7 (52.3) |
| sCSF, cc | 256.3 (62.1) | 195.9 (52.9) | 277.0 (57.8) | 252.3 (53.3) | 242.6 (59.3) |
| vCSF, cc | 45.7 (28.4) | 23.8 (11.1) | 43.7 (16.6) | 38.2 (19.4) | 41.3 (23.0) |
| pWMH*, mm3 | 2564.5 (2811.2) | 1040.0 (1252.5) | 2736.0 (1623.8) | 2563.5 (2708.0) | 4054.0 (7468.0) |
| dWMH*, mm3 | 289.5 (424.7) | 208.0 (386.5) | 138.5 (379.3) | 259.5 (225.7) | 555.0 (584.0) |
| LACN*, mm3 | 15.5 (66.0) | 14.5 (12.2) | 9.5 (55.5) | 17.5 (70.0) | 92.0 (291.0) |
| PVS*, mm3 | 45.5 (35.5) | 17.5 (9.5) | 32.5 (36.3) | 34.0 (30.0) | 44.0 (33.0) |
| Stroke*, mm3 | – | 90.0a | 393.0 (294.0)b | 531.5 (1269.0)c | 4644.5 (12963.0)d |
Data is shown as median (interquartile range).
Available in 1/40 participants.
Available in 6/52 participants.
Available in 4/140 participants.
Available in 88/155 participants AD/MCI, Alzheimer's Disease and Mild Cognitive Impairment; ALS, Amyotrophic Lateral Sclerosis; FTD, Frontotemporal Dementia; PD, Parkinson's Disease; VCI, Vascular Cognitive Impairment; ST-TIV, supratentorial total intracranial volume; NAWM, normal appearing white matter; NAGM, normal appearing gray matter; sCSF, sulcal cerebrospinal fluid; vCSF, ventricular cerebrospinal fluid; pWMH, periventricular white matter hyperintensities; dWMH, deep white matter hyperintensities; LACN, lacunes; PVS, perivascular spaces.