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. 2020 Aug 11;8:440. doi: 10.3389/fped.2020.00440

Table 2.

Available data on butyrate concentrations in human milk.

References N° samples N° mothers Min value
(mM)
Max value
(mM)
Methods
Maria et al. (68) 150 30 0.1 0.23 GC-MS utilizing a lipase assisted sample preparation (deuterated butyric acid (BA-D7) as an internal standard)
Schwab et al. (70) 19 19 1.36 5.7 HPLC-RI with external standard
Prentice et al. (69) 102 102 0.0 0.4 H-NMR and GC-MS
Dai et al. (67) 180 60 0.29 0.48 Methyl esterification of SCFAs and GC analysis

GC-MS, gas chromatography-mass spectrometry; HPLC-RI, high performance liquid chromatography with refractive index detection; H-NMR, nuclear magnetic resonance spectroscopy; SCFAs, short chain fatty acids.