TABLE 2.
Most enriched DAVID clusters and supporting functional categories (enrichment score ES > 1.3) among the genes presenting significant maternal immune activation-by-sex interaction effect.
| aCategory | Category identifier and name | P-value | bFDR P-value |
| Cluster 1 | ES = 2.74 | ||
| KEGG | ssc05320:Autoimmune thyroid disease | 2.90E-06 | 4.50E-04 |
| BP | GO:000250∼Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | 1.90E-03 | 3.40E-01 |
| KEGG | ssc04514:Cell-adhesion molecules (CAMs) | 2.30E-03 | 3.20E-02 |
| KEGG | ssc05323:Rheumatoid arthritis | 4.80E-03 | 5.60E-02 |
| KEGG | ssc05164:Influenza A | 2.00E-02 | 1.70E-01 |
| Cluster 2 | ES = 1.9 | ||
| BP | GO:0051050∼Positive regulation of transport | 4.40E-03 | 3.50E-01 |
| BP | GO:0051049∼Regulation of transport | 4.50E-03 | 3.20E-01 |
| BP | GO:0050801∼Ion homeostasis | 1.30E-02 | 3.60E-01 |
| BP | GO:0048878∼Chemical homeostasis | 2.80E-02 | 4.80E-01 |
| BP | GO:0030001∼Metal ion transport | 4.50E-02 | 5.70E-01 |
| Cluster 3 | ES = 1.75 | ||
| BP | GO:0048871∼Multicellular organismal homeostasis | 2.00E-04 | 3.70E-01 |
| Cluster 4 | ES = 1.69 | ||
| BP | GO:0061564∼Axon development | 6.40E-05 | 1.70E-01 |
| BP | GO:0007420∼Brain development | 1.30E-03 | 3.10E-01 |
aBP, biological process; KEGG, KEGG pathway. bFalse discovery rate adjusted P-value.