TABLE 3.

Enriched informative categories (NES > |1.3|) using GSEA among the genes based on the overall maternal immune activation-by-sex interaction.

aCategory	Category identifier and name	bNES	P-value	cFDR P-value
KEGG	ssc04080:Neuroactive ligand receptor interaction	−1.84	<1.0E-10	8.3E-02
KEGG	ssc04912:GnRH signaling pathway	−1.83	<1.0E-10	9.9E-02
MF	GO:0005179∼Hormone activity	−1.80	<1.0E-10	2.2E-01
BP	GO:0006970∼Response to osmotic stress	−1.79	<1.0E-10	3.5E-01
BP	GO:0019221∼Cytokine mediated signaling pathway	−1.33	9.1E-02	5.4E-01
BP	GO:1901385∼Regulation of voltage gated calcium channel activity	−1.37	1.2E-01	5.4E-01
KEGG	ssc04020:Calcium signaling pathway	−1.34	1.2E-01	5.4E-01
BP	GO:0085029∼Extracellular matrix assembly	−1.31	1.8E-01	5.5E-01

^aMF, molecular function; KEGG, KEGG pathway; BP, biological process. ^bNormalized enrichment score; negative values indicate genes under-expression in CON females relative to males but over-expression in MPA females relative to males. ^cFalse discovery rate adjusted P-value.