TABLE 4.
Representative genes differentially expressed (FDR-adjusted P-value < 0.1) between pigs from control (CON) relative to PRRSV-treated (MPA) gilts.
| Gene symbol | Gene name | aCON-MPA | P-value | bFDR P-value |
| IGHG | IgG heavy chain | –4.74 | 1.1E-31 | <1.0E-10 |
| IFITM3 | Interferon induced transmembrane prot 3 | –1.27 | 7.6E-11 | 6.2E-08 |
| IGF2 | Insulin-like growth factor 2 | 1.28 | 8.1E-07 | 2.7E-04 |
| PAQR6 | Progestin and adipoQ receptor family member 6 | –1.02 | 1.9E-06 | 5.6E-04 |
| RGS8 | Regulator of G protein signaling 8 | –0.88 | 8.6E-06 | 2.0E-03 |
| NDNF | Neuron-derived neurotrophic factor | –1.27 | 1.5E-05 | 3.3E-03 |
| HS3ST5 | Heparan sulfate-glucosamine 3-sulfotransferase 5 | –1.24 | 3.5E-05 | 6.8E-03 |
| CTSC | Cathepsin C | –1.03 | 4.1E-05 | 7.7E-03 |
| SPP1 | Secreted phosphoprotein 1 | –0.89 | 4.1E-05 | 7.7E-03 |
| TACC1 | Transforming acidic coiled-coil-containing protein 1 | –1.55 | 5.5E-05 | 9.7E-03 |
| IFITM1 | Interferon induced transmembrane prot 1 | –1.15 | 7.4E-05 | 1.2E-02 |
| ALDH1A1 | Aldehyde dehydrogenase 1 fam mem A1 | 0.79 | 9.7E-05 | 1.5E-02 |
| PLEKHD1 | Pleckstrin homology coiled-coil domain-containing D1 | –0.99 | 5.6E-04 | 6.5E-02 |
| HERC5 | HECT and RLD domain-containing E3 ubiquitin ligase 5 | –1.05 | 5.7E-04 | 6.6E-02 |
| IAPP | Islet amyloid polypeptide | –1.36 | 7.0E-04 | 7.7E-02 |
| ISLR | Immunoglobulin superfamily contain leucine rich repeat | 1.13 | 8.3E-04 | 8.5E-02 |
| ANKRD24 | Ankyrin repeat domain 24 | –0.73 | 8.7E-04 | 8.9E-02 |
| MAP2K7 | Mitogen-activated protein kinase kinase 7 | –0.64 | 9.9E-04 | 1.0E-01 |
aLog2[fold change] between CON and MPA pigs. bFalse discovery rate adjusted P-value.