TABLE 9.
Clusters of enriched functional categories (enrichment score ES > 1.3) among the genes in modules presenting a significant correlation with maternal immune activation (MPA) relative to control within males using DAVID.
| aCategory | Category identifier and name | P-value | bFDR P-value |
| MODULE | Gray60 (low expression in MPA) | ||
| Cluster 1 | ES = 14.5 | ||
| KEGG | Ssc05010:Alzheimer’s disease | 1.3E-18 | 9.1E-17 |
| KEGG | Ssc05012:Parkinson’s disease | 9.8E-18 | 4.7E-16 |
| Cluster 2 | ES = 7.32 | ||
| MF | GO:0016651∼oxidoreductase activity, acting on NAD(P)H | 3.6E-10 | 1.5E-07 |
| MF | GO:0003954∼NADH dehydrogenase activity | 3.4E-09 | 6.8E-07 |
| Cluster 3 | ES = 6.41 | ||
| BP | GO:0042775∼mitochondrial ATP synthesis electron | 4.0E-10 | 8.6E-07 |
| BP | GO:0046034∼ATP metabolic process | 8.0E-10 | 8.7E-07 |
| BP | GO:0009116∼nucleoside metabolic process | 7.8E-08 | 9.4E-06 |
| MODULE | Light yellow (low expression in MPA) | ||
| Cluster 1 | ES = 4.18 | ||
| KEGG | ssc03010:Ribosome | 3.7E-06 | 5.9E-05 |
| BP | GO:0006412∼translation | 9.5E-06 | 1.7E-02 |
| Cluster 1 | ES = 2.49 | ||
| BP | GO:0007006∼mitochondrial membrane organization | 5.1E-04 | 7.8E-02 |
| BP | GO:0007007∼inner mitochondrial organization | 1.1E-02 | 3.5E-01 |
aBP, biological process; MF, molecular function; KEGG, KEGG pathway. bFalse discovery rate adjusted P-value.