Table 5.

Evolution of symptoms in neonates who did not go on to receive a topical antibiotic therapy according to treatment arm (n = 68 neonates, 87 affected eyes).

	Euphrasia (n = 41 eyes)	Missing data	Placebo (n = 46 eyes)	Missing data	p-valuea
Ocular discharge
Ocular discharge at baseline	39 (95.1%)b	-	46 (100.0%)	-	0.99
Resolution during intervention	34 (89.5%)	1	39 (86.7%)	1	0.83
Time to resolution		-		-	0.16
24–48 h	22 (64.7%)		31 (79.5%)
72–96 h	12 (35.3%)		8 (20.5%)
Relapse during intervention	13 (38.2%)	1	6 (15.8%)	1	0.03
Ocular discharge at 96 h	12 (30.8%)	2	12 (27.7%)	2	0.73
Reddening
Reddening at baseline	27 (65.9%)	-	15 (33.3%)	1	0.003
Resolution during intervention	26 (96.3%)	-	15 (100.0%)	-	0.99
Time to resolution		-		-	0.34
24–48 h	24 (92.3%)		12 (80.0%)
72–96 h	2 (7.7%)		3 (20.0%)
Relapse or first signs during intervention	3 (7.9%)	3	8 (18.2%)	2	0.17
Reddening at 96 h	1 (2.6%)	2	2 (4.5%)	2	0.99
Tearing
Tearing at baseline	24 (60.0%)	1	25 (56.8%)	2	0.77
Resolution during intervention	23 (100.0%)	1	24 (96.0%)	-	0.99
Time to resolution		-		-	0.99
24–48 h	19 (82.6%)		19 (79.2%)
72–96 h	4 (17.4%)		5 (20.8%)
Relapse or first signs during intervention	18 (46.2%)	2	22 (50.0%)	2	0.73
Tearing at 96 h	5 (12.8%)	2	12 (27.3%)	2	0.10

Data are expressed as number (percentage).

^aChi-square test or Fischer test, as appropriate.

^bTwo neonates did not fill the inclusion criteria (intention-to-treat approach).